- β-
Glucocerebrosidase (also
called acid β-glucosidase, D-glucosyl-N-acylsphingosine glucohydrolase, or GCase) is an
enzyme with
glucosylceramidase activity...
- and spleen, and is
caused by a
hereditary deficiency of the
enzyme glucocerebrosidase (also
known as glucosylceramidase),
which acts on glucocerebroside...
-
monosaccharide head
group is glucose. In Gaucher's disease, the
enzyme glucocerebrosidase is
nonfunctional and
cannot break down
glucocerebroside into glucose...
-
recently been
shown to
increase activity of the
lysosomal enzyme glucocerebrosidase.
Because of this it may be a
useful therapeutic agent for both Gaucher...
-
Protalix and Pfizer.[full
citation needed] The drug, a
recombinant glucocerebrosidase used to
treat Gaucher's disease, is the
first plant-made pharmaceutical...
- LSD is Gaucher's disease,
which is due to
deficiency of the
enzyme glucocerebrosidase. Consequently, the
enzyme substrate, the
fatty acid glucosylceramide...
-
implicated in PD in
South Asian po****tions. The GBA gene
encodes for
glucocerebrosidase (GCase)
which is a
lysosomal enzyme that
breaks down glucosylceramide...
-
recently been
shown to
increase activity of the
lysosomal enzyme glucocerebrosidase, so it may be a
useful therapeutic agent for both
Gaucher disease...
-
Beutler E, West C,
Gelbart T (1992). "Polymorphisms in the
human glucocerebrosidase gene". Genomics. 12 (4): 795–800. doi:10.1016/0888-7543(92)90311-F...
- Israel.
Development of
taliglucerase alfa (Elelyso), a
recombinant glucocerebrosidase enzyme produced from
transgenic carrot cell cultures. Taliglucerase...
