-
Filaggrin (filament
aggregating protein) is a filament-****ociated
protein that
binds to
keratin fibers in
epithelial cells. Ten to
twelve filaggrin units...
-
ribosomes and
mitochondria disappear, the
cells become densely packaged with
filaggrin and
cover more surface.
After final dehydration, the cell desquamates...
- clearly. The
protein filaggrin is
believed to be
synthesized as a
giant precursor protein,
profilaggrin (>400 kDA in humans). When
filaggrin binds to keratin...
-
usually an
autosomal dominant inherited disease (often ****ociated with
filaggrin),
although a rare non-heritable
version called acquired ichthyosis exists...
-
contact dermatitis,
symptoms of
which are
indistinguishable from eczema.
Filaggrin mutations are ****ociated with
atopic eczema and may
contribute to the...
- for the
onset of
atopic dermatitis and
asthma has been
attributed to
filaggrin, a skin
precursor of
urocanic acid.
Urocanic acid is
thought to be a significant...
-
production of
filaggrin (FLG),
which increase the risk for
early onset of
atopic dermatitis and
developing asthma. However,
expression of
filaggrin protein...
- when the
biochemical basis of
antibody reactivity against keratin and
filaggrin was investigated.
Subsequent studies demonstrated that autoantibodies...
-
normally contain citrulline residues include myelin basic protein (MBP),
filaggrin, and
several histone proteins,
whereas other proteins, such as fibrin...
-
cells to the site of
pathogen invasion. A
number of
structural proteins (
filaggrin, keratin),
enzymes (e.g. proteases), lipids, and
antimicrobial peptides...
