- An
enkephalin is a
pentapeptide involved in
regulating nociception (pain sensation) in the body. The
enkephalins are
termed endogenous ligands, as they...
- Leu-
enkephalin is an
endogenous opioid peptide neurotransmitter with the
amino acid
sequence Tyr-Gly-Gly-Phe-Leu that is
found naturally in the brains...
-
short duration. It is one of the two
forms of
enkephalin, the
other being leu-
enkephalin. The
enkephalins are
considered to be the
primary endogenous ligands...
-
Lasker Award for
Basic Medical Research for the
discovery of met-
enkephalin and leu-
enkephalin. This
discovery demonstrated that
opiate drugs exert their effects...
- via
proteolyic cleavage,
produces the
enkephalin peptides [Met]
enkephalin, and to a
lesser extent, [Leu]
enkephalin. Upon cleavage, each
proenkephalin peptide...
-
receptors with
opioids as ligands. The
endogenous opioids are dynorphins,
enkephalins, endorphins,
endomorphins and nociceptin. The
opioid receptors are ~40%...
- Kosterlitz. They
isolated "
enkephalins" (from the Gr**** εγκέφαλος, cerebrum) from pig brain,
identified as Met-
enkephalin and Leu-
enkephalin. This came
after the...
-
reticularis since they also
express ACTH receptors. β-Endorphin and [Met]
enkephalin are
endogenous opioid peptides with
widespread actions in the brain. The...
- also the
primary control center for
descending pain modulation. It has
enkephalin-producing
cells that
suppress pain. The
periaqueductal gray is the gray...
- gene for the
enkephalins was
isolated and its
sequence described in 1982. The
human gene for
dynorphins (originally
called the "
Enkephalin B" gene because...
