-
Endothelins are
peptides with
receptors and
effects in many body organs.
Endothelin constricts blood vessels and
raises blood pressure. The endothelins...
-
Endothelin receptor type B, (ET-B) is a
protein that in
humans is
encoded by the
EDNRB gene.
Endothelin receptor type B is a G protein-coupled receptor...
-
Endothelin receptor type A, also
known as ETA, is a
human G protein-coupled receptor.
Endothelin receptor type A has been
shown to
interact with HDAC7A...
- is
proteolytically processed to
release endothelin 1.
Endothelin 1 is one of
three isoforms of
human endothelin.
Preproendothelin is
precursor of the peptide...
- An
endothelin receptor antagonist (ERA) is a drug that
blocks endothelin receptors.
Three main
kinds of ERAs exist: Dual ET
Receptor Antagonists, which...
-
There are at
least four
known endothelin receptors, ETA, ETB1, ETB2 and ETC, all of
which are G protein-coupled
receptors whose activation result in elevation...
-
Endothelin converting enzyme 1, also
known as ECE1, is an
enzyme which in
humans is
encoded by the ECE1 gene.
Endothelin-converting enzyme-1 is involved...
- activity) decreases.
Endothelin-1 is a
peptide (comprising 21
amino acids) that is
produced in
endothelial cells. It acts on the
endothelin receptors ETA and...
- to Hirschsprung's
disease in humans. A
mutation in the
middle of the
endothelin receptor type B (EDNRB) gene
causes lethal white syndrome when homozygous...
- hormones;
angiotensin II,
endothelin-1 and the
catecholamines (e.g. noradrenaline).[citation needed] Angiotensin-II and
endothelin-1 are
hormones that bind...
