-
Endothelins are
peptides with
receptors and
effects in many body organs.
Endothelin constricts blood vessels and
raises blood pressure. The endothelins...
- An
endothelin receptor antagonist (ERA) is a drug that
blocks endothelin receptors.
Three main
kinds of ERAs exist:
selective ETA
receptor antagonists...
-
Endothelin receptor type B, (ET-B) is a
protein that in
humans is
encoded by the
EDNRB gene.
Endothelin receptor type B is a G protein-coupled receptor...
- is
proteolytically processed to
release endothelin 1.
Endothelin 1 is one of
three isoforms of
human endothelin.
Preproendothelin is
precursor of the peptide...
-
There are at
least four
known endothelin receptors, ETA, ETB1, ETB2 and ETC, all of
which are G protein-coupled
receptors whose activation result in elevation...
-
Endothelin receptor type A, also
known as ETA, is a
human G protein-coupled receptor.
Endothelin receptor type A has been
shown to
interact with HDAC7A...
- Macitentan, sold
under the
brand name Opsumit, is an
endothelin receptor antagonist (ERA)
developed by
Actelion and
approved for the
treatment of pulmonary...
- Matsuda, Yoichi; Akiyama,
Toyoko (February 2012). "Gene
Duplication of
endothelin 3 Is
Closely Correlated with the
Hyperpigmentation of the
Internal Organs...
-
Endothelin converting enzyme 1, also
known as ECE1, is an
enzyme which in
humans is
encoded by the ECE1 gene.
Endothelin-converting enzyme-1 is involved...
-
Endothelin 2 (ET-2) is a
protein encoded by the EDN2 gene in humans. It was
first discovered in 1988 by
Yanagisawa and team and
belongs to a
family of...
