-
prostaglandins are
biosynthesized by
initial formation of a
bicyclic peroxide ("
endoperoxide")
derived from
arachidonic acid. Many
aspects of
biodegradation or aging...
-
Cyclooxygenase 1 (COX-1), also
known as prostaglandin-
endoperoxide synthase 1 (HUGO PTGS1), is an
enzyme that in
humans is
encoded by the PTGS1 gene. In...
-
Cyclooxygenase (COX),
officially known as prostaglandin-
endoperoxide synthase (PTGS), is an
enzyme (specifically, a
family of isozymes, EC 1.14.99.1) that...
- Cyclooxygenase-2 (COX-2), also
known as Prostaglandin-
endoperoxide synthase 2 (HUGO PTGS2), is an
enzyme that in
humans is
encoded by the PTGS2 gene. In...
- give the key
intermediate α-hydroxy- peroxide.
After cyclization to the
endoperoxide, the mono-anion will
undergo decomposition without luminescence, if the...
- all
sesquiterpene lactones containing an
unusual peroxide bridge. This
endoperoxide 1,2,4-trioxane ring is
responsible for
their antimalarial properties...
- An
alveolar macrophage,
pulmonary macrophage, (or dust cell) is a type of macrophage, a
professional phagocyte,
found in the
airways and at the
level of...
-
effective antimalarial drug.
Artemisinin is a
sesquiterpene lactone with an
endoperoxide bridge and has been
produced as an
antimalarial drug. The
efficacy of...
-
corresponding diols. The
intermediate of the
reaction is an
unstable endoperoxide.
Thiourea is also used in the
reductive workup of
ozonolysis to give...
-
stimulates prostaglandin E2
production by
activating COX-1 and
prostaglandin endoperoxide synthase-1 but
inhibits prostacyclin production. Additionally, expression...
