- (+)-
Discodermolide is a
polyketide natural product found to
stabilize microtubules. (+)-
discodermolide was
isolated by
Gunasekera and his co-workers at...
-
starting blocks for the
synthesis of many
targets including dictyostatin,
discodermolide and spongidepsin. Shin, Youseung; Fournier, Jean-Hugues; ****ui, Yoshikazu;...
-
chemists due to its
production of a
potent chemical compound called (+)-
discodermolide,
which has
potential therapeutic applications for
cancer treatment....
-
multidrug resistant cell lines.
Discodermolide was
initially found to have
immunosuppressive and
antifungal activities.
Discodermolide is a
polyhydroxylated alketetraene...
- has been emplo**** in many
total syntheses in the literature, such as
discodermolide Evans–Tishchenko
reaction Yang,
Jaemoon (2008). "Diastereoselective...
-
Kosan Biosciences was
acquired by Bristol-Myers
Squibb for $190M.
Discodermolide is a
recently discovered polyketide natural product found to be a potent...
-
dissoluta and the
compound derived from it is
Discodermolide.
Pomponi and
others researched if
Discodermolide could also work as an
immune suppressant and...
-
family (HSP90 inhibitors) The
cholesterol lowering agent lovastatin Discodermolide Aflatoxin Usnic acid
Anthracimycin Anthramycin Olivetolic acid (intermediate...
-
mechanisms still remain to be similar. One in
particular is called,
discodermolide. Dr.
Horwitz and her team were
interested in not only the
binding site...
-
second methyl group was
integrated by a C-methyl-transferase domain.
Discodermolide Rosenberg, Steven; DeVita,
Vincent T.; ****man,
Samuel (2005). Cancer:...
