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Dihydroorotase (EC 3.5.2.3,
carbamoylaspartic dehydrase,
dihydroorotate hydrolase) is an
enzyme which converts carbamoyl aspartic acid into 4,5-dihydroorotic...
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carbamoyl phosphate synthetase II,
aspartate carbamoyltransferase and
dihydroorotase.
Dihydroorotate dehydrogenase (DHODH)
unlike CAD and UMPS is a mono-functional...
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carbamoyl aspartic acid,
which is
cyclized into 4,5-dihydroorotic acid by
dihydroorotase. The
latter is
converted to
orotate by
dihydroorotate oxidase. The net...
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synthesis of the
pyrimidine nucleotides:
carbamoyl phosphate synthase,
dihydroorotase,
aspartate carbamoyltransferase. This must have
involved a
double fusion...
- (carbamoyl-phosphate
synthetase 2,
aspartate transcarbamylase, and
dihydroorotase) is a
trifunctional multi-domain
enzyme involved in the
first three...
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opisthokonts have a
triple fusion of
carbamoyl phosphate synthetase,
dihydroorotase, and
aspartate carbamoyltransferase that is not
present in plants, and...
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Evans DR (Jan 1990). "Mammalian
dihydroorotase:
nucleotide sequence,
peptide sequences, and
evolution of the
dihydroorotase domain of the multifunctional...
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undergoing a
condensation reaction with
carbamoyl phosphate.
Dihydroorotase and
dihydroorotase dehydrogenase then
converts N-Carbamoylaspartate to orotate...
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condenses carbamoyl phosphate with
aspartate to form uridosuccinate.
Dihydroorotase performs ring closure, a
reaction that
loses water, to form dihydroorotate...
- carbamoyl-phosphate
synthetase 1,
aspartate transcarbamylase, and
dihydroorotase Identifiers Symbol CAD NCBI gene 790 HGNC 1424 OMIM 114010
RefSeq NM_004341...
