- α-
Difluoromethyl-3,4-dihydroxyphenylalanine (DFMD, DFM-DOPA) is a DOPA
decarboxylase inhibitor.
Carbidopa Methyldopa Zbinden G, Brändle E (February 1980)...
- 1-chloro-2,2,2-trifluoroethyl
difluoromethyl ether U.S.
patent 3,535,425 - 1-chloro-2,2,2-trifluoroethyl
difluoromethyl ether as an
anesthetic agent Portal:...
-
Enflurane (2-chloro-1,1,2-trifluoroethyl
difluoromethyl ether) is a
halogenated ether.
Developed by Ross
Terrell in 1963, it was
first used clinically...
-
Desflurane (1,2,2,2-tetrafluoroethyl
difluoromethyl ether) is a
highly fluorinated methyl ethyl ether used for
maintenance of
general anesthesia. Like...
- of
cofactor pyridoxal 5'-phosphate (PLP).
Because of its
additional difluoromethyl group in
comparison to ornithine,
eflornithine is able to bind to a...
-
develop resistance to fluxapyroxad. The
compound is an
amide of 3-(
difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid
combined with an
aniline having...
-
structures 3 – 5). At the 3-position of the pyrazole, a
trifluoromethyl or
difluoromethyl provides superior selectivity and
potency compared to a fluoromethyl...
-
highly used ring
systems for
small molecule drugs by the US FDA 3-(
Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid is used in the
manufacture of...
- can
accept a
hydrogen bond from the Tyr836 (conserved) in p110α. The
difluoromethyl group can
interact with the
hydroxyl group presented on Ser774 (conserved)...
- 3-(
Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid is a
chemical compound which is used
commercially as an
intermediate to
seven fungicides which...
