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Demethylating agents are
chemical substances that can
inhibit methylation,
resulting in the
expression of the
previously hypermethylated silenced genes...
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protein shows high
similarity with the
enzyme AlkB
which oxidatively demethylates DNA. FTO is a
member of the
superfamily of alpha-ketoglutarate-dependent...
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including natural products such as
codeine (O-methylmorphine), have been
demethylated by
heating the
substance in
molten pyridine hydrochloride (melting point...
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Sarcosine oxidase is an
enzyme (EC 1.5.3.1) that
catalyzes the
oxidative demethylation of
sarcosine to
yield glycine, H2O2, 5,10-CH2-tetrahydrofolate in...
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contribute to the
metabolism of
methamphetamine via an
enzyme which N-
demethylates methamphetamine and 4-hydroxymethamphetamine into
amphetamine and 4-hydroxyamphetamine...
- it is a derivative.
Norbaeocystin is an N-
demethylated derivative of
baeocystin (itself an N-
demethylated derivative of psilocybin), and a phosphorylated...
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Asendin among others, is a
tricyclic antidepressant (TCA). It is the N-
demethylated metabolite of loxapine.
Amoxapine first received marketing approval in...
-
abbreviation of normal. Originally, the term was used to
denote the
completely demethylated form of the
parent compound. Later, the
meaning was
restricted to the...
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entactogen drug of the
methylenedioxyphenethylamine family. It is the α-
demethylated homologue of MMDA, and is also
closely related to mescaline. Alexander...
- the
enzyme methylamine—glutamate N-methyltransferase. It can also be
demethylated by
methylglutamate dehydrogenase to
regenerate glutamic acid. Shaw, WV;...
