- DNA
gyrase does play a role in
decatenation, its
function is not as
essential as
topoisomerase IV in the
decatenation of
interlinked chromosomes. Several...
- DNA
supercoil relaxation,
unknotting of single-stranded circles, and
decatenation,
provided at
least one
partner has a single-stranded region. In the case...
- The
replisome is a
complex molecular machine that
carries out
replication of DNA. The
replisome first unwinds double stranded DNA into two
single strands...
- the
genetic studies, HU was
shown to
stimulate DNA gyrase-catalyzed
decatenation of DNA in vitro. It is
unclear mechanistically how HU
modulates the activities...
- identified, however:
Topoisomerase II uses ATP
hydrolysis to
catalyze decatenation of DNA entanglements,
promoting sister chromatid resolution. Condensins...
-
supercoils in
nicked and
gapped DNA
drives DNA
unknotting and
postreplicative decatenation".
Nucleic Acids Research. 43 (15): 7229–7236. doi:10.1093/nar/gkv683...
- CZ,
Hickson ID,
Kowalczykowski SC (November 2010). "Rmi1
stimulates decatenation of
double Holliday junctions during dissolution by Sgs1-Top3". Nat Struct...
- DNA
molecules will
remain linked together. This
issue is
handled by
decatenation of the two DNA
molecules by a type II topoisomerase. Type II topoisomerases...
-
Diffley JF, Aragón L (2011). "Positive
supercoiling of
mitotic DNA
drives decatenation by
topoisomerase II in eukaryotes". Science. 331 (6022): 1328–1332. Bibcode:2011Sci...
-
degrades cyclins. The BRCT
domain is
involved in the
regulation of the
decatenation checkpoint at the end of
replication by
binding Topo IIα this arrest...
