- (KiTooltip
Inhibitor constant)
Ratio Ref.
MORTooltip μ-Opioid
receptor DORTooltip δ-Opioid
receptor KORTooltip κ-Opioid
receptor MOR:DOR:KOR
Oxycodone 18...
- Affinities,
KiTooltip Inhibitor constant Ratio MORTooltip μ-opioid
receptor DORTooltip δ-opioid
receptor KORTooltip κ-opioid
receptor MOR:DOR:KOR 0.39 nM >1...
- 120–8,300 ≥1,000 (EC50) 5.4–18.6 17 ((+)) ≥240 (EC50)
Human Rat
Human DORTooltip δ-Opioid
receptor >10,000 57,600–100,000 ≥2,900 690 (+))
Human Rat KORTooltip...
-
receptor 59
Antagonist Human MORTooltip μ-Opioid
receptor >10,000 ND
Human DORTooltip δ-Opioid
receptor >10,000 ND
Human KORTooltip κ-Opioid
receptor >10,000...
- (KiTooltip
Inhibitor constant)
Ratio Ref
MORTooltip μ-Opioid
receptor DORTooltip δ-Opioid
receptor KORTooltip κ-Opioid
receptor MOR:DOR:KOR
Morphine 1...
- (KiTooltip
Inhibitor constant)
Ratios Refs
MORTooltip μ-Opioid
receptor DORTooltip δ-Opioid
receptor KORTooltip κ-Opioid
receptor MOR:DOR:KOR
Naloxone 1...
- (KiTooltip
Inhibitor constant)
Ratio Ref
MORTooltip μ-Opioid
receptor DORTooltip δ-Opioid
receptor KORTooltip κ-Opioid
receptor MOR:DOR:KOR
Codeine 79...
- 11325–15582 Rat
MORTooltip μ-Opioid
receptor 1280 ND 420 1000+ Rat
Human DORTooltip δ-Opioid
receptor 11500 34700 Rat
KORTooltip κ-Opioid
receptor 7000 5950...
- (nM)Tooltip
Inhibitor constant)
Ratio Ref
MORTooltip μ-Opioid
receptor DORTooltip δ-Opioid
receptor KORTooltip κ-Opioid
receptor MOR:DOR:KOR 7-Hydroxymitragynine...
-
opioids at
opioid receptors (Ki, nM)
Compound MORTooltip mu-Opioid
receptor DORTooltip delta-Opioid
receptor KORTooltip kappa-Opioid
receptor Ref 3-HO-PCP 60...
