-
genetics and
molecular biology, a
corepressor is a
molecule that
represses the
expression of genes. In prokaryotes,
corepressors are
small molecules whereas...
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proteins is
higher than
corepressors, the
equilibrium is
shifted in the
agonist direction.
Conversely in
tissues where corepressors dominate, the ligand...
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between the zinc
finger DNA
binding domain and the
inhibitory domain with
corepressors, and this
interaction is
modulated by MEK". The
Journal of Biological...
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structural genes.5 The
regulators of a
given operon,
including repressors,
corepressors, and activators, are not
necessarily coded for by that operon. The location...
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factors – or
corepressors -
might bind to
these regions and
silence receptors in cells. Again,
using the
yeast two-hybrid screen, two
corepressors were isolated...
- its
inactivated form, the TR
inhibits gene
transcription by
binding corepressors. This adds an
additional level of
regulation to an
already tightly regulated...
- are
referred to as
coactivators while those that
repress are
known as
corepressors. The
mechanism of
action of
transcription coregulators is to
modify chromatin...
- coactivators,
whereas molecules that
inhibit receptor proteins are
termed corepressors. One such
example is the G protein-coupled
receptor family of receptors...
- REST
corepressor 1 also
known as
CoREST is a
protein that in
humans is
encoded by the RCOR1 gene. This gene
encodes a
protein that is well-conserved,...
-
while antagonists recruit corepressors which down
regulate gene expression. Furthermore, the
ratio of
coactivators to
corepressors is
known to vary depending...
