-
germinal centers.
Centrocytes are the non-dividing
progeny of Centroblasts, and
although they are
relatively similar in size,
centrocytes lack
distinct nucleoli...
-
histologically contain a
mixture of
centrocytes or
centroblast surrounded by non-malignant cells,
mostly T-cells. The
centrocytes,
which typically outnumber centroblasts...
- BCRs on the cell
surface and at this
stage are
referred to as
centrocytes. The
centrocytes are in a
state of
activated apoptosis and
compete for survival...
-
centroblast stage and lose the cell
marker after differentiating into
centrocytes. CD27 is an
important marker for
germinal center formation in the lymphoid...
-
Histologic comparison of cell
types in a
germinal center, H&E stain: -
Centrocytes are
small to
medium size with angulated, elongated, cleaved, or twisted...
- node None None
unknown None AICDA, BCL6, CD19, CD27, CXCR4, Mki67, MS4A1
Centrocyte unknown unknown lymph node None None
unknown None BCL6, CD19, CD83, Mki67...
-
glands by B-cells with
morphological features of
marginal zone B-cells,
centrocytes, and monocytes. Histologically, this
disorder is ****ociated with atrophy...
- form of
lymphoma in
which certain lymphocyte types, the B-cell-derived
centrocytes and centroblasts, form
lymph node follicle-like
structures prin****lly...
-
cells is
variable with
small mature lymphocytes,
cells resembling centrocytes (
centrocyte like cells), or
marginal zone/monocytoid B cells. Plasmacytoid...
-
lymphoma About 40% of
lymphomas in
adults Small "cleaved" [cleft]
cells (
centrocytes)
mixed with
large activated cells (centroblasts),
usually nodular ("follicular")...
