Definition of Alkylators. Meaning of Alkylators. Synonyms of Alkylators

Here you will find one or more explanations in English for the word Alkylators. Also in the bottom left of the page several parts of wikipedia pages related to the word Alkylators and, of course, Alkylators synonyms and on the right images related to the word Alkylators.

Definition of Alkylators

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Meaning of Alkylators from wikipedia

- relevant articles. Bifunctional alkylators Cyclophosphamide Mechlorethamine Chlorambucil Melphalan Monofunctional alkylators Dacarbazine Nitrosoureas Temozolomide...
- "First-in-human, phase I/IIa clinical study of the peptidase potentiated alkylator melflufen administered every three w****s to patients with advanced solid...
- for the effects of such agents as antitumor drugs, antibiotics, and DNA alkylators. Oxidation to a reactive quinone methide is the mechanistic basis of many...
- antineoplastic agent that is highly active toward AML, unlike more conventional alkylators like cyclophosphamide. The FLAMSA protocol is most often used as an induction...
- schematically below: Phosphorodiamidate-based, DNA-crosslinking, bis-alkylator mustards have long been used successfully in cancer chemotherapy and include...
- anticancer activity. DNA damage responses triggered by a highly cytotoxic monofunctional DNA alkylator, hedamycin, a pluramycin antitumor antibiotic...
- genes, in parallel with the expression of genes producing endogenous alkylators during the stationary phase, prevents alkylation damage to DNA and mutagenesis...
- children 3 years of age and older with radiation therapy and high-dose alkylator-based chemotherapy". J. Clin. Oncol. 23 (7): 1491–9. doi:10.1200/JCO.2005...
- 3α,20β-Hydroxysteroid Dehydrogenase with an Enzyme-Generated Affinity Alkylator: Dual Enzyme Activity at a Single Active Site". Biochemistry. 19 (22):...
- HS (2000). "Can O6-alkylguanine-DNA alkyltransferase depletion enhance alkylator activity in the clinic?" (PDF). Clinical Cancer Research. 6 (8): 2967–8...
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