Definition of Alkylators. Meaning of Alkylators. Synonyms of Alkylators
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Definition of Alkylators
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Meaning of Alkylators from wikipedia
articles. Bifunctional alkylators Cyclophosphamide Mechlorethamine Chlorambucil Melphalan Monofunctional alkylators Dacarbazine Nitrosoureas
- antineoplastic agent
that is highly active toward
more conventional alkylators
like cyclophosphamide. The FLAMSA protocol
is most often
used as an induction...
- "First-in-human, phase
I/IIa clinical study
of the peptidase potentiated alkylator melflufen administered every three
w****s to patients
- for the effects
of such agents
drugs, antibiotics, and DNA alkylators
to a reactive quinone methide
is the mechanistic basis
of age and older
with radiation therapy
and high-dose alkylator
-based chemotherapy". J. Clin. Oncol. 23 (7): 1491–9. doi:10.1200/JCO.2005...
activity. DNA damage responses triggered
by a highly cytotoxic monofunctional
, hedamycin, a pluramycin antitumor
- 3α,20β-Hydroxysteroid Dehydrogenase
with an Enzyme-Generated Affinity Alkylator
: Dual Enzyme Activity
at a Single Active
Site". Biochemistry. 19 (22):...
below: Phosphorodiamidate-based, DNA-crosslinking, bis-alkylator mustards
have long been used successfully
in cancer chemotherapy
- genes, in parallel
with the expression
of genes producing endogenous alkylators during
phase, prevents alkylation damage
to DNA and mutagenesis...
- HS (2000). "Can O6-alkylguanine-DNA alkyltransferase depletion enhance alkylator activity
in the clinic?" (PDF). Clinical Cancer
Research. 6 (8): 2967–8...
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