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Proteasomes are
protein complexes which degrade unneeded or
damaged proteins by proteolysis, a
chemical reaction that
breaks peptide bonds.
Enzymes that...
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Proteasome inhibitors (INN stem –zomib) are
drugs that
block the
action of
proteasomes,
cellular complexes that
break down proteins. They are
being studied...
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Proteasome accessory factor E (abbreviated PafE, also
known as
bacterial proteasome activator or Bpa) is an ATP-independent
proteasome activator of Mycobacterium...
- prosome,
multicatalytic proteinase (complex), MCP,
proteasome,
large multicatalytic protease,
proteasome organelle,
alkaline protease, 26S protease, tricorn...
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Proteasome subunit beta type-5 also
known as 20S
proteasome subunit beta-5 is a
protein that in
humans is
encoded by the PSMB5 gene. This
protein is one...
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Proteasome maturation protein is a
protein that in
humans is
encoded by the POMP gene. It is a short-lived
maturation factor required for 20S proteasome...
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Proteasome subunit beta type-4 also
known as 20S
proteasome subunit beta-7 (based on
systematic nomenclature) is a
protein that in
humans is
encoded by...
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peptides generated mainly from
degradation of
cytosolic proteins by the
proteasome. The MHC I:peptide
complex is then
inserted via
endoplasmic reticulum...
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affects proteins in many ways: it can mark them for
degradation via the
proteasome,
alter their cellular location,
affect their activity, and
promote or...
- lysosome, or a ubiquitin-dependent
process that
targets unwanted proteins to
proteasome. The autophagy-lysosomal
pathway is
normally a non-selective process,...
