-
Bicuculline is a phthalide-isoquinoline
compound that is a light-sensitive
competitive antagonist of
GABAA receptors. It was
originally identified in...
- It has long been
recognized that, for
neurons that are
stimulated by
bicuculline and picrotoxin, the fast
inhibitory response to GABA is due to direct...
-
endogenous and
exogenous actions of
GABAA receptor agonists.
Bemegride Bicuculline Cicutoxin Cyclothiazide DMCM FG-7142
Fipronil Flumazenil Flurothyl Gabazine...
- used for
counteracting overdoses of
sedative drugs.
Examples include bicuculline,
securinine and metrazol, and the
benzodiazepine GABAA receptor antagonist...
- TC-2216
Tebanicline UB-165
Varenicline WAY-317,538
Convulsants Anatoxin-a
Bicuculline DMCM
Flurothyl Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics...
-
Strychnine is a
strong antagonist at
ionotropic glycine receptors,
whereas bicuculline is a weak one.
Glycine is a
required co-agonist
along with glutamate...
-
binding site for GABA and
several drugs such as muscimol, gaboxadol, and
bicuculline. The
protein also
contains a
number of
different allosteric binding sites...
- PMID 21833169. Hill DR,
Bowery NG (March 1981). "3H-baclofen and 3H-GABA bind to
bicuculline-insensitive GABA B
sites in rat brain". Nature. 290 (5802): 149–52. Bibcode:1981Natur...
-
impairing substances, including: ethanol, chlorodiazepoxide, scopolamine,
bicuculline, picrotoxin, and cycloheximide.
Unlike other racetams,
nefiracetam shows...
- TC-2216
Tebanicline UB-165
Varenicline WAY-317,538
Convulsants Anatoxin-a
Bicuculline DMCM
Flurothyl Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics...
