Definition of Picrotoxin. Meaning of Picrotoxin. Synonyms of Picrotoxin

Here you will find one or more explanations in English for the word Picrotoxin. Also in the bottom left of the page several parts of wikipedia pages related to the word Picrotoxin and, of course, Picrotoxin synonyms and on the right images related to the word Picrotoxin.

Definition of Picrotoxin

Picrotoxin
Picrotoxin Pic`ro*tox"in, n. [Gr. ? bitter + toxic + -in.] (Chem.) A bitter white crystalline substance found in the cocculus indicus. It is a peculiar poisonous neurotic and intoxicant, and consists of a mixture of several neutral substances.

Meaning of Picrotoxin from wikipedia

- picrotoxin, also known as cocculin, is a poisonous crystalline plant compound, first isolated by pierre boullay in 1812. the name 'picrotoxin' is a combination
- actions are inhibited in vitro by gabaa antagonists like bicuculline and picrotoxin and by the glycine antagonist strychnine, respectively. mg2+ and dl-ap5
- including: ethanol, chlorodiazepoxide (librium), scopolamine, bicuculline, picrotoxin, and cycloheximide. studies of long term consumption of nefiracetam in
- convulsant potency was strongly correlated to in vitro affinity to the picrotoxin binding site on the gaba-a receptor complex. many gaba-a ligands are effective
- action - block inhibition, e.g. strychnine (via glycine antagonism), picrotoxin (via gaba antagonism) - increase excitation, e.g. doxapram, nikethamide
- indian climbing plant. its fruit, cocculus indicus, is the source of picrotoxin, a poisonous alkaloid with stimulant properties. the plant is large-stemmed
- by iuphar as a major criterion in the definition of gabaa receptors  picrotoxin manske, r. h. f. (1932). 'the alkaloids of fumaraceous plants. ii.
- hirsh k, wang sc. respiratory stimulant effects of ethamivan and picrotoxin. journal of pharmacology and experimental therapeutics. 1975 may;193(2):657-63