-
thyroid disease, and obesity.
Endocrine disease is
characterized by
misregulated hormone release (a
productive pituitary adenoma),
inappropriate response...
- and cell survival. As such, many
different types of
human tumors have
misregulated NF-κB: that is, NF-κB is
constitutively active.
Active NF-κB
turns on...
- disease. Many
cancers arise from the
inappropriate epigenetic effects of
misregulated methylation. However,
because these processes are at
times reversible...
-
obesity and diabetes. The
initial ****umption was that this
mutation was
misregulating FTO to
cause the
disease risk. However, it was
later shown that the...
- muscle-specific
chloride channel in type 1
myotonic dystrophy due to
misregulated alternative splicing".
Molecular Cell. 10 (1): 45–53. doi:10.1016/s1097-2765(02)00572-5...
- cell
cycle dynamics influence cell senescence,
oxidative stress, and
misregulated apoptosis (Franco et al., 2006). In particular, it is
clear that oxidative...
-
nucleus to the cytoplasm; it is
often overexpressed and its
function misregulated in
several types of cancer. By
inhibiting the XPO1 protein,
SINEs lead...
- also be
considered as a possibility, as they open up the
potential for
misregulated metabolic functions to be p****ed on from
generation to generation. Epigenetic...
-
expressed in
cells of the
human innate immune system.
These enzymes, when
misregulated, are a
major source of
mutation in
numerous cancer types. When the expression...
-
showed that in
metastatic prostate cancer cells, EphB
receptors are
misregulated in ways that
might lead to
cancer cell
invasion / metastasis. She showed...