- In
molecular biology,
endonucleases are
enzymes that
cleave the
phosphodiester bond
within a
polynucleotide chain (namely DNA or RNA). Some, such as deoxyribonuclease...
- Apurinic/apyrimidinic (AP)
endonuclease is an
enzyme that is
involved in the DNA base
excision repair pathway (BER). Its main role in the
repair of damaged...
- A
restriction enzyme,
restriction endonuclease, REase,
ENase or
restrictase is an
enzyme that
cleaves DNA into
fragments at or near
specific recognition...
- The
homing endonucleases are a
collection of
endonucleases encoded either as
freestanding genes within introns, as
fusions with host proteins, or as self-splicing...
-
Endonuclease V (endoV) is a
highly conserved endonuclease enzyme family. The
primary function of
endoV differs significantly in
prokaryotes and eukaryotes...
- Flap
endonucleases (FENs, also
known as 5'
durgs in
older references) are a
class of
nucleolytic enzymes that act as both 5'-3'
exonucleases and structure-specific...
-
displaces the RNA/DNA
initiator primer into a 5′ flap. The FEN1 5’-3’
endonuclease recognizes that the 5’ flap is displaced, and it cleaves,
creating a...
- Flap
endonuclease 1 is an
enzyme that in
humans is
encoded by the FEN1 gene. The
protein encoded by this gene
removes 5'
overhanging "flaps" (or short...
-
intron endonuclease,
transfer ribonucleate intron endoribonuclease, tRNA
splicing endonuclease,
splicing endonuclease,
tRNATRPintron endonuclease, transfer...
-
locus of activity.
Exonucleases digest nucleic acids from the ends.
Endonucleases act on
regions in the
middle of
target molecules. They are
further subcategorized...
